Recombinant Human DEFB119 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human DEFB119 protein Lys22-Pro84 (Accession# Q8N690-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 245932 |
| 蛋白编号 | Q8N690-1 |
| 预测分子量 | 33.8 kDa |
| SDS-PAGE | 35-42 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
DEFB119, also known as defensin beta 119, is a protein that belongs to the beta subfamily of defensins. These are antimicrobial peptides that play a critical role in protecting tissues and organs from infection by a variety of microorganisms. The DEFB119 gene is located on the long arm of chromosome 20 and is part of a cluster of other beta-defensin genes. This protein has been shown to have antibacterial activity and is involved in the innate immune response, particularly in the defence against bacteria, including both gram-negative and gram-positive bacteria, and fungi.
参考文献:
1.Li X, et al. (2022) Cell Rep Med. 3(12):100825. 2.Holly MK, et al. (2017) Annu Rev Virol. 4(1):369-391. 3.Radhakrishnan Y, et al. (2005) Genes Immun. 6(3):203-10.
