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Recombinant Human Carbonic Anhydrase IX/CA9 protein (rFc Tag) (HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg2449

Print datasheet

Synonyms

CA9, CAIX, carbonic anhydrase IX, CA 9, CA IX

验证数据展示

  • Purity of Recombinant Human Carbonic Anhydrase IX was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human Carbonic Anhydrase IX was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human Carbonic Anhydrase IX was greater than 90% as determined by SEC-HPLC.

    The purity of Human Carbonic Anhydrase IX was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human Carbonic Anhydrase IX protein Gln38-Asp414 (Accession# Q16790) with a rabbit IgG Fc tag at the C-terminus.
基因ID 768
蛋白编号 Q16790
预测分子量 67.2 kDa
SDS-PAGE 70-100 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CA9 (Carbonic anhydrase 9) may be involved in the control of cell proliferation and transformation and appears to be a novel specific biomarker for a cervical neoplasia. It is a tumor-associated antigen that has been shown to have diagnostic utility in identifying cervical dysplasia and carcinoma.The protein is present both on the plasma membrane and in the nucleus of cells.

参考文献:

1. Mika Hilvo, et al. (2008) J Biol Chem. 283(41):27799-27809.
2. Qi Su, et al. (2019) Cell Death Dis. 10(12):939.
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