Recombinant Human CLEC4C protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human CLEC4C protein Asn45-Ile213 (Accession# Q8WTT0-1) with a rabbit IgG Fc tag at the N-terminus. |
| 基因ID | 170482 |
| 蛋白编号 | Q8WTT0-1 |
| 预测分子量 | 47.1 kDa |
| SDS-PAGE | 50-65 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CLEC4C (C-type lectin domain family 4 member C), also known as DLEC, BDCA-2, CD303, and HECL, is a type II membrane protein that contains C-type lectin domain. The C-type lectin domain family members share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. CLEC4C is a specific surface marker of human plasmacytoid dendritic cells, centrally involved in antigen presentation and immune tolerance.
参考文献:
1.Kanazawa N, et al. (2004) Immunobiology. 209(1-2):179-90. 2.McGreal EP, et al. (2004) Mol Immunol. 41(11):1109-21. 3. Wilson NR, et al. (2022) Leuk Lymphoma. 63(1):19-30. 4.Boiocchi L, et al. (2013) Blood. 11;122(2):296-7.
