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Recombinant Human CD158G/KIR2DS5 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3719

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Synonyms

验证数据展示

  • Purity of Recombinant Human CD158G was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CD158G was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human CD158G protein His22-His245 (Accession# Q14953) with a rabbit IgG Fc tag at the C-terminus.
基因ID 3810
蛋白编号 Q14953
预测分子量 51.0 kDa
SDS-PAGE 60-85 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

KIR2DS5, a member of the KIR (killer cell immunoglobulin-like receptor) family, is a cell surface receptor expressed by subpopulations of natural killer (NK) cells and T lymphocytes. KIR2DS5 is an activating receptor that binds to a multimer of DAP12 signaling molecules and transmits activation signals through its short cytoplasmic tail. KIR2DS5 is expressed on NK cells and triggers NK cell functions, including cytotoxicity and cytokine release, upon recognition of certain polymorphisms in HLA-C molecules.

参考文献:

1. Mariella Della Chiesa, et al. (2008). Eur J Immunol. 38(8):2284-9.
2. Noriko K Steiner, et al. (2008). Immunogenetics. 60(11):655-67.
3. Jeroen H Blokhuis, et al. (2017). Immun Inflamm Dis. 5(4):461-468.