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Recombinant Human CCL8/MCP-2 protein (rFc Tag)(HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90%, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg5089

Print datasheet

Synonyms

CCL8, CCL8, MCP2, C C motif chemokine 8, C-C motif chemokine 8, CCL 8

验证数据展示

  • Purity of Recombinant Human CCL8 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CCL8 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human CCL8/MCP-2 was greater than 90% as determined by SEC-HPLC.

    The purity of Human CCL8/MCP-2 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90%, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human CCL8 protein Gln24-Pro99 (Accession# P80075) with a rabbit IgG Fc tag at the C-terminus.
基因ID 6355
蛋白编号 P80075
预测分子量 35.2 kDa
SDS-PAGE 35-40 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in 20 mM PB, 150 mM NaCl, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CCL8 (also known as MCP2) is implicated in various inflammatory processes. In bone marrow transplantation, circulating CCL8 levels positively correlate with severity of graft-versus-host disease.

参考文献:

1. Vilgelm AE, et al. (2019). Front Immunol. 10: 333.
2. Yamamoto M, et al. (2011). Exp Hematol. 39: 1101–1112.
3. Klementowicz JE, et al. (2017). J Immunol. 199: 27–32.
4. Hori T, et al. (2008). Blood, 111: 4403–4412.
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