Recombinant Human CCL23 protein (rFc Tag) (HPLC verified)
种属
Human
纯度
>90 %, SDS-PAGE
>90%, SEC-HPLC
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE >90%, SEC-HPLC |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human CCL23 protein Arg22-Asn120 (Accession# P55773-1) with a rabbit IgG Fc tag at the N-terminus. |
| 基因ID | 6368 |
| 蛋白编号 | P55773-1 |
| 预测分子量 | 38.6 kDa |
| SDS-PAGE | 36-45 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CCL23, or C-C motif chemokine ligand 23, is a protein that belongs to the CC chemokine family, which plays a crucial role in immunoregulation and inflammation. It is one of several chemokine genes clustered on the q-arm of chromosome 17. CCL23 is also upregulated in certain diseases, such as streptococcal soft tissue infection, Staphylococcus aureus bacteremia, and Pneumococcal pneumonia. Additionally, it has been implicated in various types of cancer and is considered a promising biomarker of injury in patients with ischemic conditions.
参考文献:
1.Bonaventura A. et al. (2018) J Intern Med. 283(5):476-478. 2.Kamat K. et al. (2022) Br J Cancer. 127(6):1026-1033. 3.Simats A. et al. (2018) J Intern Med. 283(5):461-475.

