Recombinant Human CCL23 protein (rFc Tag) (HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90%, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg4244

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Synonyms

C C motif chemokine 23, C-C motif chemokine 23, CCL 23, CCL-23, CCL23(19-99)



产品信息

纯度 >90 %, SDS-PAGE
>90%, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Human CCL23 protein Arg22-Asn120 (Accession# P55773-1) with a rabbit IgG Fc tag at the N-terminus.
基因ID 6368
蛋白编号 P55773-1
预测分子量 38.6 kDa
SDS-PAGE 36-45 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CCL23, or C-C motif chemokine ligand 23, is a protein that belongs to the CC chemokine family, which plays a crucial role in immunoregulation and inflammation. It is one of several chemokine genes clustered on the q-arm of chromosome 17. CCL23 is also upregulated in certain diseases, such as streptococcal soft tissue infection, Staphylococcus aureus bacteremia, and Pneumococcal pneumonia. Additionally, it has been implicated in various types of cancer and is considered a promising biomarker of injury in patients with ischemic conditions.

参考文献:

1.Bonaventura A. et al. (2018) J Intern Med. 283(5):476-478. 2.Kamat K. et al. (2022) Br J Cancer. 127(6):1026-1033. 3.Simats A. et al. (2018) J Intern Med. 283(5):461-475.

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