Recombinant Human CCL14 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human CCL14 protein Thr22-Asn93 (Accession# Q16627-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 6358 |
| 蛋白编号 | Q16627-1 |
| 预测分子量 | 34.5 kDa |
| SDS-PAGE | 34-38 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in 20 mM PB, 150 mM NaCl, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CCL14, also known as HCC-1, is a human plasma chemokine that belongs to the CC chemokine family. It was originally collected and purified from the hemofiltrate of patients with chronic renal failure. CCL14 is constitutively expressed in various tissues, including the spleen, bone marrow, liver, muscle, and intestine. CCL14 serves as a novel prognostic factor and tumor suppressor of HCC by modulating cell cycle and promoting apoptosis (PMID: 31641099), and CCL14 is a potential biomarker associated with immune cell infiltration in lung adenocarcinoma (PMID: 39030403).
参考文献:
1. Zhu M. et al. (2019). Cell Death Dis. 10(11):796. 2. Sun BE. et al. (2024). Discov Oncol.15(1):293.
