• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Recombinant Human C4BPB protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2976

Print datasheet

Synonyms

C4b binding protein beta chain, C4b-binding protein beta chain, C4BP

验证数据展示

  • Purity of Recombinant Human C4BPB was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Human C4BPB was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human C4BPB protein Ser18-Leu252 (Accession# P20851-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 725
蛋白编号 P20851-1
预测分子量 52.4 kDa
SDS-PAGE 57-80 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Complement 4 binding protein beta chain (C4BPB) is one of the two polypeptides that in humans compose plasma glycoprotein C4b-binding protein (C4BP). C4BPB binds anticoagulant vitamin K-dependent S. C4BPB controls the classical pathway of complement activation. It binds as a cofactor to the C3b/C4b inactivator (C3bINA), hydrolyzing the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a.

参考文献:

1.Rodríguez de Córdoba S. et al. (1994) Genomics. 21(3):501-509.
2.Kadavá T. et al. (2024) EMBO J. 43(14):3009-3026.