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Recombinant Human APOH protein (mFc Tag)(HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

mFc Tag

生物活性

未测试

Cat no : Eg3622

Print datasheet

Synonyms

Apolipoprotein H, Activated protein C-binding protein, Apo H, Apo-H, ApolipoproteinH

验证数据展示

  • Purity of Recombinant Human APOH was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human APOH was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human APOH was greater than 90% as determined by SEC-HPLC.

    The purity of Human APOH was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human APOH protein Gly20-Cys345 (Accession# P02749) with a mouse IgG Fc tag at the C-terminus.
基因ID 350
蛋白编号 P02749
预测分子量 62.9 kDa
SDS-PAGE 68-85 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Apolipoprotein H (ApoH), also known as beta2-glycoprotein I (B2-GPI), is a plasma glycoprotein, primarily synthesized in the liver. It has an important function in blood coagulation and clearance of apoptotic bodies from the circulation. ApoH is also an important actor of host innate immune response through its capacity to bind with high affinity to a large panel of pathogens or their proteins. APOH is classified within the candidate cardiovascular disease genes and is localized to the Golgi apparatus and is secreted into the blood.

参考文献:

1. Castro A, et al. (2010). Atherosclerosis. Mar;209(1):201-5.
2. Tan Y, et al. (2021). Front Immunol. May 4;12:604222. 
3. Hasstedt, S. J., et al. (2016). Hum Genet. Feb;135(2):201-207.
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