Recombinant Human Alpha 1B-Glycoprotein protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 | Not tested |
来源 | HEK293-derived Human Alpha 1B-Glycoprotein protein Ala22-Ser495 (Accession# P04217-1) with a rabbit IgG Fc tag at the C-terminus. |
基因ID | 1 |
蛋白编号 | P04217-1 |
预测分子量 | 78.2 kDa |
SDS-PAGE | 80-100 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Alpha-1B-glycoprotein (A1BG) is a plasma protein and is a member of the immunoglobulin superfamily. A1BG contains 474 amino acids and has 5 intrachain disulfide bonds. It has been reported that cysteine-rich secretory protein 3 (CRISP-3) is a specific and high-affinity ligand of A1BG. A1BG-CRISP-3 complex displays a similar function in protecting the circulation from a potentially harmful effect of free CRISP3 . A1BG is a protein enriched in embryonic and adult female heart tissue.
参考文献:
1.Udby L, et al. (2004) Biochemistry. 43(40):12877-86. 2.Shi W, et al. (2021) Dev Cell. 56(21):3019-3034.e7.