EXOSC7 Monoclonal antibody
EXOSC7 Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
2A4C6
验证数据展示
经过测试的应用
Positive WB detected in | Saos-2 cells, HSC-T6 cells, Caco-2 cells, LNCaP cells, HeLa cells, HEK-293 cells, NIH/3T3 cells, 4TA cells |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:5000-1:50000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
68456-1-Ig targets EXOSC7 in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Applications | WB, ELISA |
Tested Reactivity | Human, mouse, rat |
Immunogen | EXOSC7 fusion protein Ag18322 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | exosome component 7 |
Synonyms | EAP1, EXOSC7, exosome component 7, FLJ26543, hRrp42p, KIAA0116, p8, RRP42, Rrp42p |
Calculated Molecular Weight | 291 aa, 32 kDa |
Observed Molecular Weight | 35 kDa |
GenBank Accession Number | BC012831 |
Gene Symbol | EXOSC7 |
Gene ID (NCBI) | 23016 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q15024 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. EXOSC7 also named as RRP42 or EAP1 is a 291 amino acid protein, which belongs to the RNase PH family. EXOSC7 is one of the six RNase-PH domain subunits of the exosome and required for the processing of the 7S pre-RNA.
实验方案
Product Specific Protocols | |
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WB protocol for EXOSC7 antibody 68456-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |