Endoglin/CD105 Polyclonal antibody
Endoglin/CD105 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
ELISA
Conjugate
Unconjugated
验证数据展示
产品信息
The immunogen of 18471-1-AP is Endoglin/CD105 Fusion Protein expressed in E. coli.
| Tested Applications | ELISA |
| Tested Reactivity | human, mouse, rat |
| Immunogen | Endoglin/CD105 fusion protein Ag13335 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | endoglin |
| Synonyms | CD105, END, Endoglin, ENG, HHT1, ORW, ORW1 |
| Calculated Molecular Weight | 71 kDa |
| GenBank Accession Number | BC014271 |
| Gene Symbol | ENG |
| Gene ID (NCBI) | 2022 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P17813 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)