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验证数据展示

  • WB analysis of NR8383 using 83758-1-RR (same clone as 83758-1-PBS)

    WB analysis of NR8383 using 83758-1-RR (same clone as 83758-1-PBS)

    LPS and Brefeldin A treated NR8383 cells were subjected to SDS PAGE followed by western blot with 83758-1-RR (Cxcl2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83758-1-PBS in a different storage buffer formulation.

  • IF Staining of THP-1 using 83758-1-RR (same clone as 83758-1-PBS)

    IF Staining of THP-1 using 83758-1-RR (same clone as 83758-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed PMA, LPS and Brefeldin A treated THP-1 cells using Cxcl2 antibody (83758-1-RR, Clone: 240367C5 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83758-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83758-1-RR

    Affinity and Kinetic Characterization of 83758-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83758-1-RR against Mouse Cxcl2 were performed. The affinity constant is 0.517 nM.

Rat Cxcl2 Recombinant antibody, PBS Only

Cxcl2 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, ELISA
Cat No. 83758-1-PBS

产品说明书

CloneNo. 240367C5

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, ELISA

别名

240367C5, CINC-3, C-X-C motif chemokine 2, Cytokine-induced neutrophil chemoattractant 3, Macrophage inflammatory protein 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

83758-1-PBS targets Cxcl2 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 chemokine (C-X-C motif) ligand 2
别名 240367C5, CINC-3, C-X-C motif chemokine 2, Cytokine-induced neutrophil chemoattractant 3, Macrophage inflammatory protein 2
计算分子量11 kDa
观测分子量10 kDa
GenBank蛋白编号NM_053647.1
基因名称 Cxcl2
Gene ID (NCBI) 114105
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP30348
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CXCL2 is a member of the CXC subfamily, which encodes secreted proteins involved in immunoregulatory and inflammatory processes. CXCL2 is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. CXCL2 plays an critical role in maintaining cancer-induced macrophage infiltration and the resulting mechanical hypersensitivity and persistent spontaneous nociception (PMID: 36754246).