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验证数据展示

  • WB analysis using 84591-1-RR (same clone as 84591-1-PBS)

    WB analysis using 84591-1-RR (same clone as 84591-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84591-1-RR (CXCR6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84591-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 84591-1-RR (same clone as 84591-1-PBS)

    IHC staining of mouse brain using 84591-1-RR (same clone as 84591-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84591-1-RR (CXCR6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84591-1-PBS in a different storage buffer formulation.

  • IF Staining of human tonsillitis using 84591-1-RR (same clone as 84591-1-PBS)

    IF Staining of human tonsillitis using 84591-1-RR (same clone as 84591-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human tonsillitis tissue using CXCR6 antibody (84591-1-RR, Clone: 241662E5 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84591-1-PBS in a different storage buffer formulation.

  • IF Staining of human lung cancer using 84591-1-RR (same clone as 84591-1-PBS)

    IF Staining of human lung cancer using 84591-1-RR (same clone as 84591-1-PBS)

    Immunofluorescent analysis of un-fixed human lung cancer tissue using CXCR6 antibody (84591-1-RR, Clone: 241662E5 ) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 84591-1-PBS in a different storage buffer formulation.

CXCR6 Recombinant monoclonal antibody, PBS Only

CXCR6 Uni-rAb® Recombinant Antibody for WB, IHC, IF/ICC, IF-P, Indirect ELISA
Cat No. 84591-1-PBS

产品说明书

CloneNo. 241662E5

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, IF-P, Indirect ELISA

别名

241662E5, BONZO, CD186, CDw186, CXC R6

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

84591-1-PBS targets CXCR6 in WB, IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, IF-P, Indirect ELISA Application Description
经测试反应性 human
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 chemokine (C-X-C motif) receptor 6
别名 241662E5, BONZO, CD186, CDw186, CXC R6
计算分子量 39 kDa
观测分子量45 kDa
GenBank蛋白编号BC033584
基因名称 CXCR6
Gene ID (NCBI) 10663
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDO00574
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CXCR6, or C-X-C chemokine receptor 6, is a G protein-coupled receptor with seven transmembrane domains that belong to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. CXCR6 is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signaling pathway that regulates T lymphocyte migration to various peripheral tissues such as the liver, spleen red pulp, intestine, lungs, and skin. CXCR6 plays a crucial role in immunosurveillance through its interaction with epithelial cells and certain subpopulations of intratumor dendritic cells (DC), particularly DC3, which express CXCL16 at the membrane.

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