验证数据展示
产品信息
84664-3-PBS targets COMMD4 as part of a matched antibody pair:
MP01475-1: 84664-3-PBS capture and 84664-2-PBS detection (validated in Cytometric bead array)
MP01475-2: 84664-3-PBS capture and 84664-1-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
经测试应用 | WB, Cytometric bead array, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | COMMD4 fusion protein Ag34904 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | COMM domain containing 4 |
别名 | 242175E4, COMM domain containing 4, COMMD 4 |
观测分子量 | 22 kDa |
GenBank蛋白编号 | BC068998 |
基因名称 | COMMD4 |
Gene ID (NCBI) | 54939 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9H0A8 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
COMMD4 is a protein-coding gene belonging to the COMMD family and is highly expressed in non-small cell lung cancer (NSCLC) and hepatocellular carcinoma (HCC) (PMID: 36249824). It has 3 isoforms and has been shown to control NF-κB activity and regulate the activity of cullin-RING E3 ubiquitin ligases (PMID: 32439936).