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Host
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Species Reactivity
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Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 84519-4-RR (same clone as 84519-4-PBS)

    WB analysis using 84519-4-RR (same clone as 84519-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84519-4-RR (CD55 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84519-4-PBS in a different storage buffer formulation.

Mouse CD55 Recombinant antibody, PBS Only

CD55 Recombinant Antibody for WB, Indirect ELISA
Cat No. 84519-4-PBS

产品说明书

CloneNo. 241808C10

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

WB, Indirect ELISA

别名

DAF-GPI, Daf1, Daf, Complement decay-accelerating factor, GPI-anchored, Cd55a

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

84519-4-PBS targets CD55 in WB, Indirect ELISA applications and shows reactivity with mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 mouse
免疫原 FusionProtein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD55 antigen
别名 DAF-GPI, Daf1, Daf, Complement decay-accelerating factor, GPI-anchored, Cd55a
计算分子量43kDa
观测分子量58-70 kDa
GenBank蛋白编号NM_010016.3
基因名称 CD55
Gene ID (NCBI) 13136
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ61475
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD55, also known as DAF, is a glycosylphosphatidylinositol (GPI)-anchored surface glycoprotein that is widely distributed on blood, stroma, epithelial, and endothelial cells (PMID: 7517044; 29503741). It can also exist as a soluble form in plasma, urine, saliva, tears, and synovial fluids (PMID: 29503741). CD55 is a complement regulatory protein (PMID: 2469439; 7517044). It inhibits formation of the C3 convertases through binding to C3b and C4b. It also binds the alternate pathway convertase C3bBb, the classical pathway convertase and C4b2a to accelerate their decay (PMID: 17289551). CD55 also serves as a receptor for coxsackieviruses B1, B3, and B5 and several enteroviruses (PMID: 7538177; 7517044). The observed molecular weight of mature CD55 varies between 50 to 100 kDa depending on the cell type. Different sizes of CD55 might be caused by alternative splicing or different glycosylation patterns (PMID: 29503741).