验证数据展示
经过测试的应用
Positive IHC detected in | mouse spleen tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
应用 | 推荐稀释比 |
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Immunohistochemistry (IHC) | IHC : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
85620-4-RR targets CD134/OX40 in IHC, ELISA applications and shows reactivity with mouse samples.
经测试应用 | IHC, ELISA Application Description |
经测试反应性 | mouse |
免疫原 | Recombinant protein 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | tumor necrosis factor receptor superfamily, member 4 |
别名 | CD134, Tnfrsf4, Ox40, OX40 antigen, OX40L receptor |
计算分子量 | 30 kDa |
GenBank蛋白编号 | NM_011659.2 |
基因名称 | CD134 |
Gene ID (NCBI) | 22163 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P47741 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CD134 (OX40) is a member of the TNFR-superfamily of receptors. Predominantly expressed on activated T cells, CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule. CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmunity (PMID: 26215166). CD134 can interact with TRAF2, TRAF3, and TRAF5.
实验方案
Product Specific Protocols | |
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IHC protocol for CD134/OX40 antibody 85620-4-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |