Caspase 7/p20/p11 Polyclonal antibody
Caspase 7/p20/p11 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy CASP7 Ready-To-Use IHC Kit. CASP7 primary antibody included.
发表文章中的应用
| WB | See 3 publications below |
产品信息
10459-1-AP targets Caspase 7/p20/p11 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA |
| Cited Applications | WB |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Immunogen | Caspase 7/p20/p11 fusion protein Ag0670 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | caspase 7, apoptosis-related cysteine peptidase |
| Synonyms | Apoptotic protease Mch 3, CASP 7, CASP7, Caspase 7, Caspase 7/p20/p11, Caspase7, CMH 1, ICE LAP3, ICE like apoptotic protease 3, MCH3 |
| Calculated Molecular Weight | 303 aa, 34 kDa |
| GenBank Accession Number | BC015799 |
| Gene Symbol | CASP7 |
| Gene ID (NCBI) | 840 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P55210 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Caspase 7(CASP7), like caspases 3 and 6, contains a short prodomain and, upon apoptotic induction, the 35 kDa proform is converted into a 32 kDa intermediate or preactive form which is further processed into two active subunits consisting of the p20 or large (18 kDa) subunit and the p10 or small (11 kDa) subunit and it is present in the brain, which is up-regulated and activated after traumatic injury(PMID:15953353). Caspase-7 is classified as a member of the subgroup of cysteine proteases most related to the Caenorhabditis elegans factor CED-3, which also includes caspase-3, -6, and -9(PMID:9426061). The protein is involved in the activation cascade of caspases responsible for apoptosis execution.
发表文章
| Species | Application | Title |
|---|---|---|
Ann Transl Med Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma | ||
J Pharm Pharmacol Maackiain suppresses the development of cervical cancer via AMPK priming autophagy | ||
Phytother Res Agrimoniin is a dual inhibitor of AKT and ERK pathways that inhibit pancreatic cancer cell proliferation |