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AMHR2 Polyclonal antibody

AMHR2 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat No : 25888-1-AP

Print datasheet

Synonyms

AMH type II receptor, AMHR, AMHR2, MIS type II receptor, MISR2, MISRII, MRII

验证数据展示

  • IHC staining of human testis using 25888-1-AP

    IHC staining of human testis using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 25888-1-AP (AMHR2 Antibody) at dilution of 1:100 (under 40x lens).

  • IHC staining of mouse brain using 25888-1-AP

    IHC staining of mouse brain using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 25888-1-AP (AMHR2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human testis using 25888-1-AP

    IHC staining of human testis using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 25888-1-AP (AMHR2 Antibody) at dilution of 1:100 (under 10x lens).

  • IHC staining of mouse brain using 25888-1-AP

    IHC staining of mouse brain using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 25888-1-AP (AMHR2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human ovary tumor using 25888-1-AP

    IHC staining of human ovary tumor using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 25888-1-AP (AMHR2 Antibody) at dilution of 1:100 (under 40x lens).

  • IHC staining of human ovary tumor using 25888-1-AP

    IHC staining of human ovary tumor using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 25888-1-AP (AMHR2 Antibody) at dilution of 1:100 (under 10x lens).

经过测试的应用

Positive IHC detected inhuman testis tissue, human ovary tumor tissue, mouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

25888-1-AP targets AMHR2 in IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IHC, ELISA
Tested Reactivity human, mouse
Immunogen AMHR2 fusion protein Ag22473 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name anti-Mullerian hormone receptor, type II
Synonyms AMH type II receptor, AMHR, AMHR2, MIS type II receptor, MISR2, MISRII, MRII
Calculated Molecular Weight 573 aa, 63 kDa
GenBank Accession NumberBC126316
Gene Symbol AMHR2
Gene ID (NCBI) 269
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ16671
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Anti-Mullerian hormone (Amh) is the key factor in the regression of the Mullerian ducts that is secreted by the Sertoli cells of the testis. As a member of the transforming growth factor β family, Amh signals through a heterodimeric receptor complex consisting of two type I and two types II serine/threonine kinases receptors (J. Klatting, et. al, 2007). On ligand binding, Type II receptors phosphorylate and activate Type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. The Amh type II receptor (Amhr2) confers the specificity and is initially expressed in the coelomic epithelium next to the Mullerian ducts in both males and females (Zhan, y. et. al, 2006).

实验方案

Product Specific Protocols
IHC protocol for AMHR2 antibody 25888-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols