验证数据展示
产品信息
86146-1-PBS targets ALOX15B in WB, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | ALOX15B fusion protein Ag3741 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | arachidonate 15-lipoxygenase, type B |
别名 | 15 lipoxygenase 2, 15 LO 2, 15 LOX 2, 15 LOX B, 15-lipoxygenase 2 |
计算分子量 | 676 aa, 76 kDa |
观测分子量 | 67-75 kDa |
GenBank蛋白编号 | BC035217 |
基因名称 | ALOX15B |
Gene ID (NCBI) | 247 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | O15296 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating (ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes (ALOX15, ALOX15B). ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms. (PMID:24373925).