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验证数据展示

  • WB analysis of mouse lung using 85349-1-RR (same clone as 85349-1-PBS)

    WB analysis of mouse lung using 85349-1-RR (same clone as 85349-1-PBS)

    mouse lung tissue were subjected to SDS PAGE followed by western blot with 85349-1-RR (AGER/RAGE antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85349-1-PBS in a different storage buffer formulation.

  • WB analysis of pig lung using 85349-1-RR (same clone as 85349-1-PBS)

    WB analysis of pig lung using 85349-1-RR (same clone as 85349-1-PBS)

    pig lung tissue were subjected to SDS PAGE followed by western blot with 85349-1-RR (AGER/RAGE antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85349-1-PBS in a different storage buffer formulation.

  • Affinity of 85349-1-RR

    Affinity of 85349-1-RR

    Biolayer interferometry (BLl) kinetic assays of 85349-1-RR against Human AGER/RAGE were performed. The affinity constant is 0.489 nM.

AGER/RAGE Recombinant monoclonal antibody, PBS Only

AGER/RAGE Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 85349-1-PBS

产品说明书

CloneNo. 242714G12

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, pig

应用

WB, Indirect ELISA

别名

AGER, RAGE, 242714G12, Advanced glycosylation end product-specific receptor

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy AGER/RAGE Ready-To-Use IHC Kit. AGER/RAGE primary antibody included.

产品信息

85349-1-PBS targets AGER/RAGE in WB, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, pig
免疫原

CatNo: Eg3860

Product name: Recombinant Human AGER/RAGE protein (rFc Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-rFc

Tag: C-rFc

Domain: 23-342 aa of BC020669

Sequence: AQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQLVVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYSCVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLA

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 advanced glycosylation end product-specific receptor
别名 AGER, RAGE, 242714G12, Advanced glycosylation end product-specific receptor
计算分子量 404 aa, 43 kDa
观测分子量43 kDa
GenBank蛋白编号BC020669
基因名称 AGER
Gene ID (NCBI) 177
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ15109
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The receptor for advanced glycation end products (RAGE) is a cell surface transmembrane multiligand receptor, also known as Ager, is a multiligand member of the immunoglobulin superfamily. It has many isoforms and is predominantly expressed in the lung. AGER expression is upregulated in many diseases such as Alzheimer's disease, diabetes mellitus, atherosclerosis, and rheumatoid arthritis (PMID: 35099614).

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