验证数据展示
Planning an IHC experiment? We recommend our IHCeasy ABCA3 Ready-To-Use IHC Kit. ABCA3 primary antibody included.
产品信息
83018-1-RR targets ABCA3 in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | ABCA3 fusion protein Ag24749 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| 别名 | ABC-C transporter, ABCA 3, ABC3, ABC C transporter, 230194C12 |
| GenBank蛋白编号 | BC140895 |
| 基因名称 | ABCA3 |
| Gene ID (NCBI) | 21 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q99758 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ABCA3 belongs to the ATP-binding cassette (ABC) transporter superfamily. ABCA3, which is expressed in alveolar type II pneumocytes and localizes predominantly to the limiting membrane of lamellar bodies, is critical for synthesis of surfactant(PMID: 17267394). Mutation of the ABCA3 gene causes fatal surfactant deficiency in newborns(PMID: 15044640).