验证数据展示
产品信息
| Product name | Human B7-H3/CD276 Antibody Pair Set |
| Tests | 10×96 well plate |
| Assay type | Sandwich |
| Range | 46.88-3000 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 80381 |
| Specificity | Please see the product datasheet |
| Entrez Gene ID | 80381(Q5ZPR3) |
| Alternate Names | CD276 molecule, B7 homolog 3, CD276 antigen, CD276, 4Ig B7 H3, UNQ309/PRO352, B7H3, Costimulatory molecule, B7 H3 |
背景信息
B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor. Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy. In addition to the membrane form, B7-H3 can also exist as a soluble form (sB7-H3) generated either through alternative splicing or cleavage from the cell surface, and the serum level of sB7-H3 has been correlated with prognosis in various malignancies.
产品特性
- Optimization: The use of matched antibody pairs that have undergone rigorous screening and validation can significantly reduce the time required for development.
- Flexible Packaging: The availability of multiple specifications allows for the detection needs of various sample quantities to be met.
- Economic: This product offers cost-effective solutions for researchers who want to save on their budget while exploring unique sample detection systems in their assays.
- Natural Sample Testing: The product has undergone thorough testing using natural samples.
运输与储存
| Shipping | The product is shipped at 2-8℃. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20℃. Do not use past expiration date. |