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Recombinant Human CCL27 protein (rFc Tag)(HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90%, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg2461

Print datasheet

Synonyms

C C motif chemokine 27, CC chemokine ILC, C-C motif chemokine 27, CCL 27, CCL-27

验证数据展示

  • Purity of Recombinant Human CCL27 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CCL27 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human CCL27 was greater than 90% as determined by SEC-HPLC.

    The purity of Human CCL27 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90%, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human CCL27 protein Phe25-Gly112 (Accession# Q9Y4X3) with a rabbit IgG Fc tag at the N-terminus.
基因ID 10850
蛋白编号 Q9Y4X3
预测分子量 37.3 kDa
SDS-PAGE 34-40 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CCL27 (also called ESkine, ALP, ILC, or CTACK) is a chemokine predominantly expressed by skin keratinocytes. In the healthy skin, CCL27 expression was predominantly detected in keratinocytes of the epidermis and hair follicles (HF) in both humans and mice. CCL27 expression is suppressed in the lesional skin of various skin inflammatory diseases such as psoriasis, hidradenitis suppurativa (HS), and alopecia areata .

参考文献:

1.Davila, Micha L et al. (2022) iScience. 25(6):104426.
2.Zhong, Wenlong et al. (2020) Oncoimmunology. 9(1):1776060.