Recombinant Human NKG2C/CD159c protein (rFc Tag)
种属
Human
纯度
>85 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >85 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human NKG2C protein Ile94-Leu231 (Accession# P26717) with a rabbit IgG Fc tag at the N-terminus. |
| 基因ID | 3822 |
| 蛋白编号 | P26717 |
| 预测分子量 | 43.0 kDa |
| SDS-PAGE | 47-60 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
The NKG2C is a heterodimeric receptor, consisted of two type II proteins and is a member of the C-type lectin-like family. Similar to the other activating NKG2 receptors, the NKG2C has a negatively charged residue (either a lysine or an arginine) in its transmembrane domain. NKG2C is an activating receptor that recognizes HLA-E in complex with leader sequence peptides. The gene encoding NKG2C (killer-cell lectin-like receptor C2, KLRC2) is present at different copy numbers in the genomes of different individuals.
参考文献:
1. Siemaszko, Jagoda et al. Archivum immunologiae et therapiae experimentalis vol. 71,1 9. 10 Mar. 2023, 2. Cao, Kai et al. Frontiers in immunology vol. 9 2444. 23 Oct. 2018.
