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Recombinant Rat CD90 protein (rFc Tag) (HPLC verified)

种属

Rat

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg3463

Print datasheet

Synonyms

Thy1, Thy-1, Thy-1 antigen, Thy-1 membrane glycoprotein

验证数据展示

  • Purity of Recombinant Rat CD90 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Rat CD90 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Rat CD90 was greater than 90% as determined by SEC-HPLC.

    The purity of Rat CD90 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Rat CD90 protein Gln20-Cys130 (Accession# P01830) with a rabbit IgG Fc tag at the C-terminus.
基因ID 24832
蛋白编号 P01830
预测分子量 39.0 kDa
SDS-PAGE 42-50 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

THY1 (CD90) is a 25-37-kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored cell surface protein. It is usually expressed on thymocytes, mesenchymal stem cells, hematopoietic stem cells, natural killer cells, neurons, endothelial cells, renal glomerular mesangial cells, follicular dendritic cells, fibroblasts, and myofibroblasts. It has been found to regulate cell adhesion, migration, apoptosis, axon growth, cell-cell and cell-matrix interactions, T-cell activation, and fibrosis. Several reports have shown that CD90 has an important role in cancer in regulating cancer cell proliferation, metastasis, and angiogenesis. CD90 is a pan-innate lymphoid cells (ILC) marker. THY1 is a critical regulator of cell adhesion and communication, cell-ECM interaction and the immune and nervous systems.

参考文献:

1.Kumar A, et al. (2016) Tumour Biol. 37(9):11611-11622.
2.Schroeder JH, et al. (2023) Front Immunol. 14:1113735.
3.Rege TA, Hagood JS. (2006) FASEB J. 20(8):1045-54.
4.Saalbach A, et al. (2005) Oncogene. 24(29):4710-20.
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