Recombinant Mouse Semaphorin 4D/CD100 protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse Semaphorin 4D protein Phe24-Arg733 (Accession# O09126) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 20354 |
| 蛋白编号 | O09126 |
| 预测分子量 | 105.1 kDa |
| SDS-PAGE | 110-150 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD100 (also known as SEMA4D), a 150 kDa homodimer, belongs to the family of immune semaphorins. CD100 is a protein from the semaphorin family with important roles in the vascular, nervous and immune systems. It may be found as a membrane bound dimer or as a soluble molecule originated by proteolytic cleavage. CD100 is expressed by most cells of the hematopoietic system, including lymphoid cells such as B and T lymphocytes and natural killer cells, as well as myeloid cells (neutrophils, platelets, and monocytes) and endothelial cells, and its expression usually increases upon activation).
参考文献:
1.Luque MCA. et al. (2018) Front Cardiovasc Med. 5:136. 2.Luque MC. et al. (2015) Mol Immunol. 67(2 Pt B):559-67. 3.Elhabazi A. et al. (2001) J Immunol. 166(7):4341-7.
