Recombinant Mouse CD5L protein (rFc Tag) (HPLC verified)
种属
Mouse
纯度
>90 %, SDS-PAGE
>90 %, SEC-HPLC
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse CD5L protein Glu22-Val352 (Accession# Q9QWK4) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 11801 |
| 蛋白编号 | Q9QWK4 |
| 预测分子量 | 62.6 kDa |
| SDS-PAGE | 70-85 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD5-like (CD5L) is a 40-kDa soluble glycoprotein that belongs to the SRCR superfamily. CD5L is secreted primarily from macrophages in lymphoid tissues during inflammatory response.CD5L modulates the activity of macrophages in a wide spectrum of settings, including the pathogenesis of several infectious and inflammatory processes. CD5L plays important roles in many diseases, such as metabolic syndrome, acute kidney injury as well as cardiac rejection.
参考文献:
1.Sanjurjo L. et al. (2018) Front Immunol. 9:480. 2.Sanchez-Moral L. et al. (2023) EBioMedicine. 91:104555. 3.LaFargue CJ. et al. (2023) Nat Commun. 14(1):2407. 4.Oskam N. et al. (2023) Proc Natl Acad Sci U S A. 120(50):e2311265120. 5.Yang H. et al. (2024) Autoimmunity. 57(1):2201412.
