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Recombinant Mouse CD98/SLC3A2 protein (rFc Tag)(HPLC verified)

种属

Mouse

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg1547

Print datasheet

Synonyms

4F2 cell-surface antigen heavy chain, 4F2hc, Amino acid transporter heavy chain SLC3A2, CD98, Mdu1

验证数据展示

  • Purity of Recombinant Mouse CD98 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse CD98 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Mouse CD98/SLC3A2 was greater than 90% as determined by SEC-HPLC.

    The purity of Mouse CD98/SLC3A2 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Mouse CD98 protein Ala100-Ala526 (Accession# P10852-1) with a rabbit IgG Fc tag at the N-terminus.
基因ID 17254
蛋白编号 P10852-1
预测分子量 74.8 kDa
SDS-PAGE 75-100 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CD98 (SLC3A2) is a solute carrier family protein that is a component of the amino acid transporter and pairs with another solute carrier family protein, such as L-type amino acid transporter 1 (LAT1/SLC7A5) or cystine/glutamate transporter (xCT/SLC7A11). CD98 is known to play a role in delivering amino acids into and out of cells as an amino acid transporter. CD98 is highly upregulated in various cancer cells and promotes cancer cell survival, migration, invasion, angiogenesis and drug resistance.

参考文献:

1. Lee Y. et al. (2019). Nat Struct Mol Biol. 26:510–517.
2. Xia P. et al. (2023). Front Oncol. 13:1251100.
3. Lim K. et al. (2024). Cancer Immunol Immunother. 73(11):231.
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