Recombinant Mouse CD84 protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse CD84 protein Lys22-Val221 (Accession# Q18PI6-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 12523 |
| 蛋白编号 | Q18PI6-1 |
| 预测分子量 | 48.8 kDa |
| SDS-PAGE | 52-65 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD84, also known as SLAMF5, is a member of the CD2 subfamily of the immunoglobulin receptor superfamily. CD84 is a single-chain type-I glycoprotein composed of two extracellular Ig-like domains, a hydrophobic transmembrane region, and a cytoplasmic domain. It is broadly expressed on almost all leukocyte subsets. CD84 functions as a homophilic adhesion molecule, whose signaling can activate or inhibit leukocyte function depending on the cell type and its stage of activation or differentiation.
参考文献:
1. de la Fuente MA. et al. (1997). Blood. 90(6):2398-405. 2. Cuenca M. et al. (2019). Clin Immunol. 204:43-49. 3. Rabani S. et al. (2024). Cell Rep. 43(11):114920.
