Recombinant Mouse C-Reactive Protein/CRP protein (hFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
hFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse CRP protein His20-Ser225 (Accession# NP_031794.3) with a human IgG1 Fc tag at the C-terminus. |
| 基因ID | 12944 |
| 蛋白编号 | NP_031794.3 |
| 预测分子量 | 49.1 kDa |
| SDS-PAGE | 48-52 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
C-reactive protein (CRP) is an acute-phase serum protein predominately synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein that belongs to the pentraxin family of proteins. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.
参考文献:
1. Pepys MB, et al. (2003) C-reactive protein: a critical update.111(12):1805-12. 2. Black S, et al. (2004) C-reactive Protein.279(47):48487-90.
