验证数据展示
产品信息
| Product name | Human VISTA/C10orf54 Antibody Pair Set |
| Tests | 10×96 well plate |
| Assay type | Sandwich |
| Range | 0.156-10 ng/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 64115 |
| Specificity | Please see the product datasheet |
| Entrez Gene ID | 64115(Q9H7M9) |
| Alternate Names | Platelet receptor Gi24, UNQ730/PRO1412, C10orf54, PP2135, GI24, SISP1 |
背景信息
VISTA (V-domain Ig suppressor of T cell activation), also known as C10orf54, B7-H5, PD-1H and Dies1, is a member of the immune checkpoints of the B7 family that shares significant homology with PD-L1 and PD-L2. VISTA is predominantly expressed on haematopoietic cells, myeloid cells, and weakly expressed on T cells. It can act as a ligand expressed on antigen presenting cells (APCs), and also functions as an coinhibitory receptor for CD4+ T cells. VISTA exerts negative regulatory functions by suppressing the activation, proliferation, and cytokine secretion of T cells. VISTA plays an important role in tumor progression and immune escape and can be used as a predictor for diagnosis or immunotherapy of cancer.
产品特性
- Optimization: The use of matched antibody pairs that have undergone rigorous screening and validation can significantly reduce the time required for development.
- Flexible Packaging: The availability of multiple specifications allows for the detection needs of various sample quantities to be met.
- Economic: This product offers cost-effective solutions for researchers who want to save on their budget while exploring unique sample detection systems in their assays.
- Natural Sample Testing: The product has undergone thorough testing using natural samples.
运输与储存
| Shipping | The product is shipped at 2-8℃. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20℃. Do not use past expiration date. |
