验证数据展示
产品信息
| Product name | Human TNFSF15 Antibody Pair Set |
| Tests | 10×96 well plate |
| Assay type | Sandwich |
| Range | 78.1-5000 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 9966 |
| Specificity | Please see the product datasheet |
| Entrez Gene ID | 9966(O95150) |
| Alternate Names | TL1, TL1A, TNF ligand related molecule 1, TNFSF15, VEGI, VEGI192A |
背景信息
Tumor necrosis factor ligand superfamily member 15 (TNFSF15) is also named as TL1 and VEGI. And it belongs to the tumor necrosis factor family. It is a receptor for TNFRSF25 and TNFRSF6B. VEGI induced degradation of IκB alpha, and nuclear translocation of p65 subunit of NFκB by activating NFκB. TL1A mediates activation and apoptosis of NFκB in DR3-expressing cell lines. Overexpression by cancer cells of a secretable VEGI fusion protein resulted in abrogation of xenograft tumor progression. The isoforms show endothelial cell-specific expression and are generated from a 17 kb human gene by alternative splicing. In addition, VEGI can inhibit vascular endothelial growth and angiogenesis (in vitro).
产品特性
- Optimization: The use of matched antibody pairs that have undergone rigorous screening and validation can significantly reduce the time required for development.
- Flexible Packaging: The availability of multiple specifications allows for the detection needs of various sample quantities to be met.
- Economic: This product offers cost-effective solutions for researchers who want to save on their budget while exploring unique sample detection systems in their assays.
- Natural Sample Testing: The product has undergone thorough testing using natural samples.
运输与储存
| Shipping | The product is shipped at 2-8℃. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20℃. Do not use past expiration date. |
