Recombinant Human PMCH protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human PMCH protein Ile22-Val165 (Accession# P20382) a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 5367 |
| 蛋白编号 | P20382 |
| 预测分子量 | 42.4 kDa |
| SDS-PAGE | 44-50 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
The orexigenic neuropeptide melanin-concentrating hormone (MCH), a product of PMCH, is an important mediator of energy homeostasis. PMCH is expressed predominantly in neurons of the lateral hypothalamic area and the incerto hypothalamic area, which project throughout the brain. PMCH is also expressed in some peripheral tissues, such as the testes, although at lower levels than in the brain. PMCH plays an important role in determining energy balance during early development.
参考文献:
1.Mul JD. et al. (2010) Am J Physiol Endocrinol Metab. 298(3):E477-E488. 2.Mul JD. et al. (2013) PLoS One. 8(3):e60214. 3.Bertolesi GE. et al. (2019) Pigment Cell Melanoma Res. 32(4):510-527.
