Recombinant Human NCR3/NKp30 protein (rFc Tag)(HPLC verified)
种属
Human
纯度
>90 %, SDS-PAGE
>90 %, SEC-HPLC
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human NCR3 protein Leu19-Gly135 (Accession# O14931-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 259197 |
| 蛋白编号 | O14931-1 |
| 预测分子量 | 38.4 kDa |
| SDS-PAGE | 41-55 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
NCR3 (natural cytotoxicity triggering receptor 3) is part of the natural cytotoxicity receptors (NCRs), which play a crucial role in the immune system, particularly in the function of natural killer (NK) cells. NCR3 is a cell membrane receptor of NK cells that is activated by binding of extracellular ligands, including BAG6 and NCR3LG1. NCR3 is involved in the immune response by facilitating the lysis of tumor cells. It interacts with the T-cell receptor CD3-zeta (CD247).
参考文献:
1. Barrow AD, et al. (2019) Front Immunol. May 7;10:909. 2. Koch J, et al. (2013) Trends Immunol. Apr;34(4):182-91. 3. Hudspeth K, et al. (2013) Front Immunol. Mar 20;4:69.
