Recombinant Human KIR2DL5/CD158f1 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human KIR2DL5 protein His22-His238 (Accession# Q8N109) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 57292 |
| 蛋白编号 | Q8N109 |
| 预测分子量 | 49.6 kDa |
| SDS-PAGE | 55-70 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
KIR2DL5, also known as CD158f1, is a member of the human killer cell immunoglobulin-like receptor (KIR) family. KIR2DL5 has two extracellular Ig-like domains of the D0 and D2 type, a structural configuration that was previously unique to KIR2DL4. KIR2DL5 is expressed by subpopulations of NK cells and T cells. KIR2DL5 inhibits the activity of NK cells thus preventing cell lysis.
参考文献:
1.Vilches C. et al. (2000). J Immunol. 164(11):5797-5804. 2.Cisneros E. et al. (2012). Front Immunol. 3:289. 3.Ren X. et al. (2022). J Clin Invest. 132(22):e163620.
