验证数据展示
产品信息
| Product name | Human IL-11 Antibody Pair Set |
| Tests | 10×96 well plate |
| Assay type | Sandwich |
| Range | 3.13-200 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 3589 |
| Specificity | Please see the product datasheet |
| Entrez Gene ID | 3589(P20809) |
| Alternate Names | Adipogenesis inhibitory factor, AGIF, IL 11, IL11, interleukin 11, Oprelvekin |
背景信息
IL-11 is a multifunctional cytokine produced by a variety of cells, which regulates hematopoiesis, bone function and cytoprotecting in the gut. As a member of the glycoprotein (GP) 130 cytokine family, IL-11 can activate the JAK-STAT3 pathway. Its pleiotropic effect is based on both anti-inflammatory and pro-inflammatory effects. The anti-inflammatory effect is downregulating the macrophage function by inhibiting the IL-1β, IL-12 and NO production. The pro-inflammatory effect is inducing the initial CD4+ T cells to differentiate into Th17 cells, and causing the inflammatory response in the multiple sclerosis. IL-11 is related to inflammation and cancer since its transmembrane co-receptor IL-11Rα has been shown to overexpress in lung cancer, colorectal cancer, gastric cancer, breast cancer, prostate cancer and osteosarcoma.
产品特性
- Optimization: The use of matched antibody pairs that have undergone rigorous screening and validation can significantly reduce the time required for development.
- Flexible Packaging: The availability of multiple specifications allows for the detection needs of various sample quantities to be met.
- Economic: This product offers cost-effective solutions for researchers who want to save on their budget while exploring unique sample detection systems in their assays.
- Natural Sample Testing: The product has undergone thorough testing using natural samples.
运输与储存
| Shipping | The product is shipped at 2-8℃. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20℃. Do not use past expiration date. |
