Recombinant Human IFNA5 protein (rFc Tag)(HPLC verified)
种属
Human
纯度
>90 %, SDS-PAGE
>90 %, SEC-HPLC
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human IFNA5 protein Leu22-Glu189 (Accession# P01569) with a rabbit IgG Fc tag at the N-terminus. |
| 基因ID | 3442 |
| 蛋白编号 | P01569 |
| 预测分子量 | 46.9 KDa |
| SDS-PAGE | 45-50 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in 0.5M arg, 30mM Tris, pH8.0. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Interferons (IFN) are a family of cytokines with potent antiviral, antiproliferative and immunomodulatory properties, classified based on their binding specificity to cell surface receptors. The mature human IFNA5, also known as IFN-alpha G, shares 40% aa sequence identity with mouse IFNA5. IFNA5 is the only IFNA subtype detected in normal liver and has been shown to induce stronger signaling and higher expression of antiviral genes than IFNA2 in hepatocytic cells.
参考文献:
1. Pestka S. et al. (1987). Annu. Rev. Biochem. 56:727. 2. Larrea E. et al. (2004). J Interferon Cytokine Res. 24:497.
