Recombinant Human Galanin protein (mFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
mFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human Galanin protein Ala20-Ser123 (Accession# P22466) with a mouse IgG Fc tag at the C-terminus. |
| 基因ID | 51083 |
| 蛋白编号 | P22466 |
| 预测分子量 | 38.1 kDa |
| SDS-PAGE | 38-45 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Galanin is expressed in the central nervous system, including the hypothalamus, pituitary, and the spinal cord, and colocalizes with other neuronal peptides within neurons. It is also found in various tissues such as the gastrointestinal tract and pancreas, demonstrating its importance and versatility for neuro-hormonal homeostasis. Dysregulation of galanin and its related peptides has been implicated in various neuroendocrine conditions such as nociception, Alzheimer's disease, seizures, eating disorders, alcoholism, diabetes, and spinal cord conditions.
参考文献:
1.Duan J. et al. (2022). Nat Commun. 13(1):1364. 2.Zhu S. et al. (202). Front Endocrinol (Lausanne). 13:1019943.
