Recombinant Human Cystatin SN/CST1 protein (rFc Tag)(HPLC verified)
种属
Human
纯度
>90 %, SDS-PAGE
>90 %, SEC-HPLC
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human Cystatin SN protein Trp21-Ser141 (Accession# P01037) with a rabbit IgG Fc tag at the N-terminus. |
| 基因ID | 1469 |
| 蛋白编号 | P01037 |
| 预测分子量 | 41.5 kDa |
| SDS-PAGE | 39-45 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CST1, or cystatin SN, is a human gene encoding a secreted protein belonging to the type 2 cystatin superfamily, which includes CST1, CST2, CST3, CST4 and CST5. These proteins are cysteine proteinase inhibitors found in various human fluids and secretions where they appear to have protective functions. CST1 is specifically found in saliva, tears, urine and seminal fluid and plays a role in inhibiting the activity of cysteine proteases. CST1 has been implicated in several pathological processes, including tumour invasion and metastasis.
参考文献:
1.Yang J. et al. (2022) BMC Cancer. 22(1):589. 2.Li D. et al. (2023) Oncogene. 42(2):83-98. 3.Jiang J. et al. (2015) Tumour Biol. 36(5):3903-10. 4.Zhang L. et al. (2024) Sci Rep. 14(1):4985.
