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Recombinant Human CDCP1 protein (rFc Tag) (HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg2574

Print datasheet

Synonyms

CD318, CUB domain-containing protein 1, Membrane glycoprotein gp140, SIMA135, Subtractive immunization M plus HEp3-associated 135 kDa protein

验证数据展示

  • Purity of Recombinant Human CDCP1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CDCP1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human CDCP1 was greater than 90% as determined by SEC-HPLC.

    The purity of Human CDCP1 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human CDCP1 protein Phe30-Thr667 (Accession# Q9H5V8) with a rabbit IgG Fc tag at the C-terminus.
基因ID 64866
蛋白编号 Q9H5V8
预测分子量 98.1 kDa
SDS-PAGE 105-120 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CDCP1, also called CD318, TRASK, and SIMA 135, is a transmembrane protein containing three CUB domains within the extracellular region and a hexalysine stretch within the cytoplasmic region. CDCP1 is a novel marker for hematopoietic stem cells. CDCP1 is overexpressed in a variety of malignant tumors including respiratory tumors, digestive system cancers, hematological malignancies and urogenital cancers. It has been recognized as a promising diagnostic biomarker and a potential target for disrupting cancer progression.

参考文献:

1.Conze T, et al. (2003)  Ann N Y Acad Sci. 996:222-6. 
2.Wortmann A, et al. (2009) IUBMB Life. 61(7):723-30. 
3.Khan T, et al. (2021) Cancer Res. 1;81(9):2259-2269.
4.Qi X, et al. (2022) Life Sci. 15;301:120600.
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