Recombinant Human CD97 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human CD97 protein Gln21-Gln398 (Accession# P48960-2) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 976 |
| 蛋白编号 | P48960-2 |
| 预测分子量 | 67.4 kDa |
| SDS-PAGE | 75-100 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD97 is a member of the seven-trans-membrane subfamily of the class B G protein-coupled receptor (GPCR) group of the epidermal growth factor (EGF) and is present on the surface of lymphocytes, monocytes, macrophages, dendritic cells, granulocytes, and smooth muscle, being a dimeric glycoprotein with a 75-90 kDa intracellular domain and a 28 kDa extracellular domain. It plays a vital role in cell adhesion, migration, and cell connection regulation. CD97 is expressed on T-cells, but rarely on B cells. CD97 might play key roles in cellular adhesion, through connections with other proteins of the cell surface and of the extracellular matrix.
参考文献:
1. Michael Safaee, et al. (2013) Int J Oncol. 43(5):1343-50. 2. Qiuming Su, et al. (2022) World J Surg Oncol. 20(1):382. 3. Cristiana Tanase, et al. (2020) Int J Mol Sci. 21(16):5656.
