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验证数据展示

  • WB analysis using 28632-1-AP (same clone as 28632-1-PBS)

    WB analysis using 28632-1-AP (same clone as 28632-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28632-1-AP (SLC38A1 antibody) at dilution of 1:7000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 28632-1-AP (same clone as 28632-1-PBS)

    WB analysis of HeLa using 28632-1-AP (same clone as 28632-1-PBS)

    WB result of SLC38A1 antibody (28632-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SLC38A1 transfected Jurkat cells. This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 28632-1-AP (same clone as 28632-1-PBS)

    IHC staining of mouse brain using 28632-1-AP (same clone as 28632-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28632-1-AP (SLC38A1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 28632-1-AP (same clone as 28632-1-PBS)

    IHC staining of mouse brain using 28632-1-AP (same clone as 28632-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28632-1-AP (SLC38A1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

SLC38A1 Polyclonal antibody, PBS Only

SLC38A1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 28632-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

28632-1-PBS targets SLC38A1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 SLC38A1 fusion protein Ag30088 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 38, member 1
别名
计算分子量 487 aa, 54 kDa
观测分子量54 kDa, 60-70 kDa
GenBank蛋白编号BC010620
基因名称 SLC38A1
Gene ID (NCBI) 81539
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H2H9
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC38A1 (Sodium-coupled neutral amino acid transporter 1), is also named as SNAT1, which is a symporter that cotransports short-chain neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane (PMID:20599747, PMID:10891391). Inhibition of SLC38A1 reduced tumor growth, cellular migration, invasion, and induced senescence in melanoma cells (PMID:35565278). SLC38A1 was identified as a positive regulator of mTORC1 in neurons, which promoted ischemic brain damage by mTOR-autophagy system (PMID:31552299). SLC38A1 is mainly expressed in brain and placenta.