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验证数据展示

  • WB analysis using 17245-1-AP (same clone as 17245-1-PBS)

    WB analysis using 17245-1-AP (same clone as 17245-1-PBS)

    mouse pancreas tissue was subjected to SDS PAGE followed by western blot with 17245-1-AP (SEC16B antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17245-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 17245-1-AP (same clone as 17245-1-PBS)

    IHC staining of human pancreas cancer using 17245-1-AP (same clone as 17245-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 17245-1-AP (SEC16B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17245-1-PBS in a different storage buffer formulation.

SEC16B Polyclonal antibody, PBS Only

SEC16B Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 17245-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

17245-1-PBS targets SEC16B in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag11173

Product name: Recombinant human SEC16B protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-352 aa of BC009106

Sequence: MELWAPQRLPQTRGKATAPSKDPDRGFRRDGHHRPVPHSWHNGERFHQWQDNRGSPQPQQEPRADHQQQPHYASRPGDWHQPVSGVDYYEGGYRNQLYSRPGYENSYQSYQSPTMREEYAYGSYYYHGHPQWLQEERVPRQRSPYIWHEDYREQKYLDEHHYENQHSPFGTNSETHFQSNSRNPCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQYIRDAPERDDPPASAAWSPVQAEDVSSAGPKAPMKFYIPHVPVSFGPGGQLVRVGPSSPTDGQAALVELHSMEVILNDSEEQEEMRSFSGPLIREDVHKVDIMTFCQQKAAQ

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 SEC16 homolog B (S. cerevisiae)
别名
计算分子量 71 kDa, 117 kDa
观测分子量 60-70 kDa
GenBank蛋白编号BC009106
基因名称 SEC16B
Gene ID (NCBI) 89866
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96JE7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SEC16B also known as LZTR2, RGPR-p117, is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (PMID: 17192411). SEC16B regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes (PMID:21768384). SEC16B may be involved in human obesity to possess an association between single nucleotide polymorphisms and different measures of obesity (PMID: 28413634).

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