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验证数据展示

  • WB analysis of PC-12 using 28079-1-AP (same clone as 28079-1-PBS)

    WB analysis of PC-12 using 28079-1-AP (same clone as 28079-1-PBS)

    PC-12 cells were subjected to SDS PAGE followed by western blot with 28079-1-AP (SCN1A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28079-1-PBS in a different storage buffer formulation.

SCN1A Polyclonal antibody, PBS Only

SCN1A Polyclonal Antibody for WB, Indirect ELISA
Cat No. 28079-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, rat

应用

WB, Indirect ELISA

别名

sodium channel, Pan, FEB3, GEFSP2, HBSCI, NAC1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

28079-1-PBS targets SCN1A in WB, Indirect ELISA applications and shows reactivity with human, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, rat
免疫原

CatNo: Ag25942

Product name: Recombinant human SCN1A protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 456-522 aa of NM_001165963

Sequence: MEAAQQAATATASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDEDEFQK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sodium channel, voltage-gated, type I, alpha subunit
别名 sodium channel, Pan, FEB3, GEFSP2, HBSCI, NAC1
计算分子量 229 kDa
观测分子量 229-240 kDa
GenBank蛋白编号NM_001165963
基因名称 SCN1A
Gene ID (NCBI) 6323
RRIDAB_2881054
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP35498
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Sodium channel protein type 1 subunit alpha (SCN1A) is a multi-pass membrane protein that is crucial for generating and transmitting electrical signals in neurons, thereby contributing to the sensory perception of mechanically-induced pain (PMID: 14672992). SCN1A also regulates neuronal excitability and is essential for normal brain function (PMID: 37139072; 20831750).