验证数据展示
产品信息
18156-1-PBS targets Piccolo in IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | IF-P, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | Piccolo fusion protein Ag12952 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | piccolo (presynaptic cytomatrix protein) |
别名 | |
计算分子量 | 553 kDa |
GenBank蛋白编号 | BC001304 |
基因名称 | Piccolo |
Gene ID (NCBI) | 27445 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9Y6V0 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Piccolo is a presynaptic scaffolding protein of the cytomatrix assembled at the active zone (AZ). AZ is a special region of the presynaptic plasma membrane where synaptic vesicles (SVs) fuse. It has been shown that Piccolo affects presynaptic function by negatively regulating SV exocytosis (PMID: 18519737).