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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 25479-1-AP (same clone as 25479-1-PBS)

    WB analysis using 25479-1-AP (same clone as 25479-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25479-1-AP (GIPC3-Specific antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25479-1-PBS in a different storage buffer formulation.

GIPC3-Specific Polyclonal antibody, PBS Only

GIPC3-Specific Polyclonal Antibody for WB, Indirect ELISA
Cat No. 25479-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

25479-1-PBS targets GIPC3-Specific in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 GIPC PDZ domain containing family, member 3
别名
计算分子量 34 kDa
观测分子量40 kDa
GenBank蛋白编号NM_133261
基因名称 GIPC3
Gene ID (NCBI) 126326
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8TF64
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Human PDZ domain-containing protein GIPC3 is a member of the GIPC (GAIP-interacting protein C-terminus) gene family, which is characterized by a single, conserved PDZ domain and GIPC homology (GH1 and GH2) domains. Aberrant expression of GIPC3 has been evidenced to correlate to the audiogenic seizures and sensorineural hearing loss in mouse and human (PMID: 36301034, 21326233). GIPC3 is upregulated in multiple cancer types, with a significant positive correlation of its expression with Hh signaling identified in melanoma cell lines (PMID: 34224745). This antibody is highly specific for GIPC3 protein.