Dynamitin (200-406 aa) Polyclonal antibody

dynactin-2 Polyclonal Antibody for ELISA
Cat No. 10033-1-Ig

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

ELISA

DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, DYNAMITIN, p50 dynamitin, RBP50

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy DCTN2 Ready-To-Use IHC Kit. DCTN2 primary antibody included.

产品信息

10033-1-Ig targets dynactin-2 in ELISA applications and shows reactivity with human samples.

经测试应用 ELISA Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 dynactin 2 (p50)
别名 DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, DYNAMITIN, p50 dynamitin, RBP50
计算分子量 50 kDa
GenBank蛋白编号BC000718
基因名称 Dynamitin
Gene ID (NCBI) 10540
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ13561
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believing to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, and thus extend to vesicle trafficking and membrane integrity. Dynamitin was so named because of its overexpression causes dynactin complex, which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is the MacMARCKS binding protein and residues 59-83 is responsible for calmodulin binding. This antibody is is against the N terminal 83AA of full length p50 dynamitin.

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