验证数据展示
产品信息
10033-1-Ig targets dynactin-2 in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | Recombinant Protein 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | dynactin 2 (p50) |
| 别名 | DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, DYNAMITIN, p50 dynamitin, RBP50 |
| 计算分子量 | 50 kDa |
| GenBank蛋白编号 | BC000718 |
| 基因名称 | Dynamitin |
| Gene ID (NCBI) | 10540 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q13561 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believing to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, and thus extend to vesicle trafficking and membrane integrity. Dynamitin was so named because of its overexpression causes dynactin complex, which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is the MacMARCKS binding protein and residues 59-83 is responsible for calmodulin binding. This antibody is is against the N terminal 83AA of full length p50 dynamitin.