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验证数据展示

  • WB analysis using 28676-1-AP (same clone as 28676-1-PBS)

    WB analysis using 28676-1-AP (same clone as 28676-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28676-1-AP (VPS13C antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28676-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach using 28676-1-AP (same clone as 28676-1-PBS)

    IHC staining of human stomach using 28676-1-AP (same clone as 28676-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 28676-1-AP (VPS13C antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28676-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

Mouse VPS13C Polyclonal antibody, PBS Only

VPS13C Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 28676-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

BLTP5C, Intermembrane lipid transfer protein VPS13C, Kiaa3021, PARK23, Vacuolar protein sorting-associated protein 13C

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

28676-1-PBS targets VPS13C in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag29434

Product name: Recombinant mouse VPS13C protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 3575-3699 aa of NM_177184

Sequence: GIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLENHIKKLEGEAYQFHCAVPGNKRAVLMITNRRALFIKEVEILGHMSVDWQCLFEDFVCPPEVSENLLKISVKEQGLFHKKDSAN

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 vacuolar protein sorting 13C (yeast)
别名 BLTP5C, Intermembrane lipid transfer protein VPS13C, Kiaa3021, PARK23, Vacuolar protein sorting-associated protein 13C
观测分子量 422 kDa
GenBank蛋白编号NM_177184
基因名称 Vps13c
Gene ID (NCBI) 320528
RRIDAB_2881191
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8BX70
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

VPS13 (vacuolar protein sorting 13) acts at membrane contact sites between intracellular organelles to transport lipids. There are four VPS13 family members in human - VPS13A, VPS13B, VPS13C and VPS13D. Mutations in human VPS13 genes are linked to rare neurodegenerative disorders: chorea- acanthocytosis (VPS13A), Cohen syndrome (VPS13B), predispose to early onset into Parkinson's disease (VPS13C) and lead to ataxia/spastic paraplegia (VPS13D) (PMID: 30656912).

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