UGT1A6 Polyclonal antibody
UGT1A6 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
ELISA and More (2)
Conjugate
Unconjugated
验证数据展示
发表文章中的应用
| WB | See 2 publications below |
| IHC | See 2 publications below |
产品信息
13127-2-AP targets UGT1A6 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA |
| Cited Applications | WB, IHC |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, rat |
| Immunogen | UGT1A6 fusion protein Ag3792 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | UDP glucuronosyltransferase 1 family, polypeptide A6 |
| Synonyms | GNT1, HLUGP, HLUGP1, UDPGT, UDPGT 1 6, UGT 1F, UGT1, UGT1 06, UGT1*6, UGT1.6, UGT1A6, UGT1A6S, UGT1F |
| Calculated Molecular Weight | 532 aa, 61 kDa |
| GenBank Accession Number | BC019861 |
| Gene Symbol | UGT1A6 |
| Gene ID (NCBI) | 54578 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P19224 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
UGT1A6 belongs to the UDP-glycosyltransferase family functioning to catalyze the transfer of glycosyl groups to lipophilic substrates, which play a key role in the inactivation and elimination of many endogenous and exogenous compounds. UGT1A6 is responsible for the glucuronida-tion of many xenobiotics and several drugs, like paracetamol, valproate,and deferiprone. It also metabolizes several important endogenous substrates such as serotonin. Polymorphisms exists in UGT1A6 gene. Studies have demonstrated very widespread variability in the expression of UGT1A6 in liver.
发表文章
| Species | Application | Title |
|---|---|---|
Cancer Chemother Pharmacol Evaluation of resveratrol sensitivities and metabolic patterns in human and rat glioblastoma cells. | ||
Neurotherapeutics Diffusion Efficiency and Bioavailability of Resveratrol Administered to Rat Brain by Different Routes: Therapeutic Implications. |